ACTN3 Polymorphism: Comparison Between Elite Swimmers and Runners
نویسندگان
چکیده
منابع مشابه
ACTN3 Polymorphism: Comparison Between Elite Swimmers and Runners
BACKGROUND The human ACTN3 gene encodes α-actinin-3, an actin-binding protein with a pivotal role in muscle structure and metabolism. A common genetic single nucleotide polymorphism (SNP) at codon 577 of the ACTN3 results in the replacement of an arginine (R) with a stop codon (X). The R allele is a normal functional version of the gene, whereas the X allele contains a sequence change that comp...
متن کاملNo association between ACTN3 R577X polymorphism and elite judo athletic status.
The authors compared ACTN3 R577X genotype and allele frequencies in the majority of all-time-best Spanish judo male athletes (n = 108) and 343 ethnically matched nonathletic men. No between-groups differences were found in allele (P = .077) or genotype distributions (P = .178). Thus, the R577X polymorphism was not significantly associated with the status of being an elite judo athlete, at least...
متن کاملAssociation analysis of ACE and ACTN3 in elite Caucasian and East Asian swimmers.
PURPOSE Polymorphic variation in the angiotensin-converting enzyme (ACE) and α-actinin-3 (ACTN3) genes has been reported to be associated with endurance and/or power-related human performance. Our aim was to investigate whether polymorphisms in ACE and ACTN3 are associated with elite swimmer status in Caucasian and East Asian populations. METHODS ACE I/D and ACTN3 R577X genotyping was carried...
متن کاملInvestigation of the Relationship Between a Genetic Polymorphism in ACTN3 and Elite Sport Performance Among Iranian Soccer Players
Objectives: Polymorphisms in α-actinin-3 (ACTN3) gene are considered to be important in the genetic predisposition to human athletic performance. Most of the activities in soccer such as jumping, striking the ball, and running are considered plyometric and explosive. Performance power during such activities depends on the strength of the muscles involved. Therefore, high muscle strength i...
متن کاملACTN3 R577X genotype and performance of elite middle-long distance swimmers in China
The ACTN3 gene is one of the genes that have a potential influence on physical performance. Studies have shown that the 577R genotype of ACTN3 is more prevalent in sprint athletes, while the 577X genotype is more prevalent in endurance athletes. In swimming, both power and endurance related phenotypes are equally needed for swimmers to excel at the elite level. Therefore, the ACTN3 R577X polymo...
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ژورنال
عنوان ژورنال: Sports Medicine - Open
سال: 2015
ISSN: 2199-1170,2198-9761
DOI: 10.1186/s40798-015-0023-y